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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL1XR1 All Species: 48.79
Human Site: T423 Identified Species: 71.56
UniProt: Q9BZK7 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZK7 NP_078941.2 514 55595 T423 A S A S F D S T V R L W D V D
Chimpanzee Pan troglodytes XP_521379 534 57733 T433 A S A S F D S T V X L W D V E
Rhesus Macaque Macaca mulatta XP_001101823 506 54482 T415 A S A S F D S T V R L W D V D
Dog Lupus familis XP_850905 514 55709 T423 A S A S F D S T V R L W D V D
Cat Felis silvestris
Mouse Mus musculus Q8BHJ5 514 55642 T423 A S A S F D S T V R L W D V D
Rat Rattus norvegicus Q5M7T1 339 37599 T252 C T L S G F H T R T I Y D V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516513 527 56747 T436 A S A S F D S T V R L W D V E
Chicken Gallus gallus NP_001153226 523 56567 T432 A S A S F D S T V R L W D V D
Frog Xenopus laevis Q6GPC6 522 56266 T431 A S A S F D S T V R L W D V D
Zebra Danio Brachydanio rerio Q803D2 410 46511 W323 R D K T I K M W D I S T G M C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RJ9 700 72369 T608 A S A S F D S T V R L W D V E
Honey Bee Apis mellifera XP_393667 512 56104 T420 A S A S F D S T V R L W D V E
Nematode Worm Caenorhab. elegans Q17963 376 40375 K289 L W D F S K G K T L K Q Y T G
Sea Urchin Strong. purpuratus XP_001198347 493 53832 T402 A S A S F D S T V R L W D V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FLX9 473 52879 L386 S F D K S V R L W N G I T G Q
Baker's Yeast Sacchar. cerevisiae P38262 535 59143 T433 L W S L K Q N T L L A L S I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 96.8 99 N.A. 99 21 N.A. 88.8 90.2 96.7 22.1 N.A. 55.7 74.1 21.7 79.3
Protein Similarity: 100 89.1 97.4 99.4 N.A. 99.2 32.2 N.A. 93.5 94.8 97.3 38.5 N.A. 64.5 81.5 36.7 85.8
P-Site Identity: 100 86.6 100 100 N.A. 100 26.6 N.A. 93.3 100 100 0 N.A. 93.3 93.3 0 93.3
P-Site Similarity: 100 93.3 100 100 N.A. 100 46.6 N.A. 100 100 100 13.3 N.A. 100 100 0 100
Percent
Protein Identity: N.A. N.A. N.A. 22.7 26.3 N.A.
Protein Similarity: N.A. N.A. N.A. 38.1 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 69 0 69 0 0 0 0 0 0 0 7 0 0 0 7 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 7 13 0 0 69 0 0 7 0 0 0 75 0 38 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 % E
% Phe: 0 7 0 7 69 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 7 0 0 0 7 0 7 7 7 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 7 7 7 0 7 0 % I
% Lys: 0 0 7 7 7 13 0 7 0 0 7 0 0 0 0 % K
% Leu: 13 0 7 7 0 0 0 7 7 13 69 7 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 7 % Q
% Arg: 7 0 0 0 0 0 7 0 7 63 0 0 0 0 0 % R
% Ser: 7 69 7 75 13 0 69 0 0 0 7 0 7 0 0 % S
% Thr: 0 7 0 7 0 0 0 82 7 7 0 7 7 7 0 % T
% Val: 0 0 0 0 0 7 0 0 69 0 0 0 0 75 7 % V
% Trp: 0 13 0 0 0 0 0 7 7 0 0 69 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _